What happens to the efficacy of lidocaine after 4 weeks if not refrigerated?

Lidocaine, when not refrigerated, can undergo significant degradation over time due to environmental factors such as temperature, light, and humidity. After four weeks at room temperature, the efficacy of lidocaine is known to decrease, which is why the correct statement indicates a reduction to about 66% efficacy. This reduction can impact its effectiveness in clinical applications, making it critical for healthcare providers to store medications properly to maintain their potency. The process of degradation may include changes in chemical structure, which diminishes the drug's ability to provide the intended numbing effect. Therefore, understanding the importance of proper medication storage is essential for ensuring optimal therapeutic outcomes.