What is the predominant risk factor for developing primary varicose veins?

The predominant risk factor for developing primary varicose veins is genetics. This reflects the strong hereditary component observed in the condition, as individuals with a family history of varicose veins are significantly more likely to develop them. The genetic predisposition can influence the structural integrity of the veins, including factors such as the connective tissue quality and the function of valves within the veins.

While obesity, age, and prolonged sitting all contribute to the risk of varicose veins, they do so primarily as secondary factors that can exacerbate a pre-existing genetic tendency. For instance, obesity increases pressure on the veins in the lower limbs, age may affect the elasticity of veins, and prolonged sitting can hinder proper blood circulation. However, these factors do not establish the underlying predisposition to the condition as genetics does, making it the primary risk factor in the development of varicose veins.