What symptoms can local anesthetic toxicity cause?

Local anesthetic toxicity is primarily characterized by central nervous system effects, which commonly manifest as neurological symptoms. Facial tingling is associated with sensory disturbances that can occur as the anesthetic interferes with normal nerve signal transmission. As toxic levels of local anesthetics are reached, seizures may also occur due to excitation of the central nervous system.

Seizures result from hyperactivity of neuronal activity, which can happen when the anesthetic disrupts the normal equilibrium between excitatory and inhibitory neurotransmission. The presence of tingling sensations indicates the impact on peripheral nerves, while seizures indicate more severe central nervous system involvement. These symptoms can escalate quickly and are critical for healthcare providers to recognize in order to manage the situation appropriately and prevent further complications.

The other symptoms listed, while possible in different contexts, do not directly manifest as a primary presentation of local anesthetic toxicity or are not as typically observed. Increased blood pressure and enhanced reflexes may occur due to the stress response or other concurrent conditions, but they are not hallmark indicators of toxicity related to local anesthetics. Drowsiness and confusion, although somewhat relevant, are more general and can be attributed to various factors not specific to local anesthetic toxicity.